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Solid Phase Peptide Synthesis
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Solid Phase Peptide Synthesis

Peptide Synthesis Resins

Since Solid Phase Peptide Synthesis was first proposed by Robert Bruce Merrifield, the method of synthetic peptides became more popular than liquid phase peptide synthesis because of high efficiency. This method could assemble a peptide chain rapidly through successive reactions of amino acid derivatives on an insoluble support.
 
Solid Phase Peptide Synthesis-SEPLITE
 
The original peptide antibiotics are also biosynthesized and extracted from the culture of polymyxa or aeruginosa. Another synthetic method of peptides is chemical synthesis, which is divided into liquid phase chemical synthesis and solid phase chemical synthesis. The liquid phase method is mainly used for the synthesis of short peptides. The solid phase synthesis method can be used to prepare long-chain peptides, cyclic peptides, and complex. Peptide. The solid phase method is divided into a Boc method and an Fmoc method. It requires the solid phase synthesis of the carrier to achieve the growth of the peptide chain by means of stepwise amino acid condensation. The advantages of solid phase synthesis are ease of purification, shortening of the synthesis cycle, and ease of automation.

Solid phase peptide synthesis(SPPS) support consists of small, polymeric resin beads functionalized with reactive group such as amine or hydroxyl groups, which link to systhesis peptide chain step by step.

Solid phase peptide synthesis(SPPS) resins is insoluble in all common solvents but swells well in most organic solvents. Better swelling degree is benefit for the reaction yields, but for short peptide easy to synthesis, lower swelling degree will be suitable and it will be good at saving solvent.

Solid phase peptide synthesis Resins are rich in variety, complete in specifications and stable in performance.

Typical Applications

  • Solid phase synthesis of Bivalirudin
  • Solid phase synthesis of Eptifibatide
  • Solid phase synthesis of Exenatide
  • Solid phase synthesis of Liraglutide
  • Solid phase synthesis of thymopentin
  • Solid phase synthesis of Thymalfasin
  • Solid phase synthesis of Buserelin
  • Solid phase synthesis of Goserelin
  • Solid phase synthesis of Octreotide
  • Solid phase synthesis of Calcitonin

Our Customized Service

We also have good experiences in research and develop the amine acid pre-loading peptide resins, and we have extended resin backbone to hydrophilic matrix, such as DEG series, TEG series, PEG series. Welcome to ask for Sunresin!

 

Solid Phase Peptide Synthesis

Separate Hydrophobic or Weak Hydrophobic Substances
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Bio-Pharmaceutical & Life Science
Modern biopharmaceutical technologies typically use biological microbial fermentation...
Chemical Industry
Purification of chemical compounds has become a vital part of most industrial processes.
Drinking Water Treatment
Drinking water is essential to life. Every day every human being has to drink and use water for food preparation.
Food & Beverage Industries
Food is closely related to everyone, and the finishing of food comes from people's relentless pursuit...
Hydrometallurgy & Mining
Hydrometallurgy is a technique for extractive metallugry involving the three general area...
Direct Lithium Extraction (DLE)
Sunresin is the major DLE lithium sorbent producer in China which mainly used for extraction lithium from salar brine and geothermal brine etc with high efficiency.
Industry Water Treatment
There are many uses of water in industry and, in most cases, the used water also needs treatment to render...
Plant Extraction
Plant Extraction is a process to gather the trace bioactive compounds from the tissue of a plant.
VOCs Treatment
With the widespread use of chemical products in the industry, more and more organic...
Wastewater Treatment
Wastewater treatment is the process of converting wastewater into an effluent that can be discharged
Latest News
27
2023 11
 Sunresin Participates in Morgan Stanley 22nd Annual Asia-Pacific Summit
Sunresin, a leading technology company, was invited to attend Morgan Stanley's 22nd Asia-Pacific Summit in Singapore from November 15th to 16th. This summit is a pivotal conference for institutional investors in the Asia-Pacific region.
25
2023 11
 Sunresin won the 2023 Forbes Asia Top 200 and was invited to attend the award ceremony
On November 21, the Forbes Asia Best Under A Billion Forum & Awards Dinner was held in Manila, Philippines. We are proud to announce that Dr. Gao Yuejing, chairwoman of Sunresin, has been invited to attend the award ceremony and has received for the second time this honor since 2020.
29
2023 09
 Announcement: Dr Simona Serban Has Joined Sunresin As Global Application Director for Life Science Division
We are very proud to announce that Dr Simona Serban has joined Sunresin as Global Application Director for Life Science division. Simona comes with more than a decade experience in applications of resins in the Life Science
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Sunresin Park,No.135, jinye Road, Xi’an Hi-tech Industrial Development Zone, Shaanxi-710076, China
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+86-29-89182091